药物详细合成路线

Name	E-3174;EXP-3174
Chemical Name	2-Butyl-4-chloro-1-[2-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]imidazole-5-carboxylic acid
CAS	124750-92-1
Related CAS
Formula	C22H21ClN6O2
Structure
Formula Weight	436.90467
Stage	III 期临床
Company	Bristol-Myers Squibb (Originator)
Activity/Mechanism	CARDIOVASCULAR DRUGS, Hypertension, Treatment of, Angiotensin AT1 Antagonists
Syn. Route	1

Route 1 exp3174 is obtained from dup 753 (entry number: 162288). List of intermediates No. Reference 1:     duncia, j.v.; carini, d.j.; chiu, a.t.; pierce, m.e.; price, w.a.; smith, r.d.; wells, g.j.; wong, p.c.; wexler, r.r.; johnson, a.l.; timmermans, p.b.m.w.m.; dup 753. drugs fut 1991, 16, 4, 305.

来源:药化网

作者:药化小编

摘要:本文合成路线介绍的是药物中文名氯沙坦；英文名E-3174;EXP-3174；CAS[124750-92-1]

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