药物详细合成路线
| Name | E-3174;EXP-3174 | | Chemical Name | 2-Butyl-4-chloro-1-[2-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]imidazole-5-carboxylic acid | | CAS | 124750-92-1 | | Related CAS | | | Formula | C22H21ClN6O2 | | Structure |  | | Formula Weight | 436.90467 | | Stage | III 期临床 | | Company | Bristol-Myers Squibb (Originator) | | Activity/Mechanism | CARDIOVASCULAR DRUGS, Hypertension, Treatment of, Angiotensin AT1 Antagonists | | Syn. Route | 1 | | Route 1 | | exp3174 is obtained from dup 753 (entry number: 162288). | | |  | | List of intermediates | No. | | | Reference 1: duncia, j.v.; carini, d.j.; chiu, a.t.; pierce, m.e.; price, w.a.; smith, r.d.; wells, g.j.; wong, p.c.; wexler, r.r.; johnson, a.l.; timmermans, p.b.m.w.m.; dup 753. drugs fut 1991, 16, 4, 305. |
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来源:药化网
作者:药化小编
摘要:本文合成路线介绍的是药物中文名氯沙坦；英文名E-3174;EXP-3174；CAS[124750-92-1]
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