2016年12月19日，FDA批准上市Clovis Oncology公司的胰腺癌新药 rucaparib。
| Cas No. |
459868-92-9 |
SDF |
|
| Synonyms |
Rucaparib phosphate,AG-14699,AG 014699 |
| Chemical Name |
8-fluoro-2-(4-((methylamino)methyl)phenyl)-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one phosphate |
| Canonical SMILES |
OP(O)(O)=O.FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1 |
| Formula |
C19H18FN3O.H3PO4 |
M.Wt |
421.36 |
| Solubility |
>21.1mg/mL in DMSO |
Storage |
Store at -20°C |
合成路线参考：
合成文献：
Organic Process Research & Development, 16(12), 1897-1904; 2012
U.S. Pat. Appl. Publ., 20060063926, 23 Mar 2006
PCT Int. Appl., WO2000042040, 20 Jul 200
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